Monensin Sodium – MIB #57

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Revised June 2017

Approved Brands

  1. Coban Premix contains monensin (as monensin sodium) at 200 g/kg (Elanco)
  2. Rumensin Premix contains monensin (as monensin sodium) at 200 g/kg (Elanco)
  3. Monensin Premix contains monensin (as monensin sodium) at 200 g/kg (Bio Agri Mix LP)

Approved for use

In meal or pellet feed for broiler chickens, growing turkeys and cattle approved with the use of all premixes.
In thixotropic liquid supplements for cattle approved with the use of all premixes.

Approved claims

For broiler chickens – Claim 1
For growing turkeys – Claim 2
For beef cattle – Claim 3
For cattle – Claim 4
For pasture cattle – Claim 5
For lactating dairy cows – claims 6 and 8
For dry and lactating dairy cows – claim 7

Claim 1: As an aid in the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. mitis, and E. maxima in broiler chickens.

Level of Drug

100 mg/kg (0.01%) of monensin in the complete feed.

Directions:

Feed this medicated feed continuously as sole ration to broiler chickens.

Warning:

  1. Do not feed to replacement or laying chickens.
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Do not use this medicated feed for treatment of outbreaks of Coccidiosis.
  2. Do not allow dogs, horses, other equines, or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
  3. Poultry consuming monensin should not be treated with products containing tiamulin. Severe growth depression may occur.
  4. May be used in feeds containing the following pellet binding agents: bentonite (2%), attapulgite (2%), kaolin (2.5%), lignin sulfonate (4%), carboxymethylcellulose (0.1%), or Agri-Colloid (Required on premix and supplement labels only.)

Claim 2: As an aid in the prevention of coccidiosis caused by Eimeria adenoeides, E. meleagrimitis, and E. gallapavonis in growing turkeys.

Level of Drug:

100 mg/kg (0.01%) of monensin in the complete feed.

Directions:

Feed this medicated feed continuously as the sole ration to growing turkeys.

Warning:

  1. Do not feed to replacement, laying or breeding turkeys.
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Do not use this medicated feed for treatment of outbreaks of coccidiosis.
  2. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestions of monensin by these species has been fatal.
  3. Poultry consuming monensin should not be treated with products containing tiamulin. Severe growth depression may occur.
  4. Some species of turkey coccidia may be monensin tolerant.
  5. May be used in feeds containing the following pellet-binding agents: bentonite (2%), attapulgite (2%), kaolin (2.5%), lignin sulfonate (4%), carboxymethylcellulose (0.1%), or Agri-Colloid (Required on premix and supplement labels only.)

Claim 3: For improved feed efficiency in beef cattle (steers and heifers) fed in confinement for slaughter.

Level of Drug:

Choose one of the feeding programs provided below:

Option 1: From start to market weight:
  1. 33 mg/kg (0.0033%) of monensin in the complete diet approved with the use of Monensin Premix.
  2. 33 mg/kg to 48 mg/kg (0.0033% to 0.0048%) of monensin in the complete diet approved with the use of all premixes.

Note: (Required on feed labelsfor option 1 (b))

1. The Rumensin Premix data used to support this claim for feed efficiency for a dose range of 33 to 48 mg/kg was derived from a meta-analysis, including 11 studies and more than 11,000 animals. This analysis demonstrated an additional improvement in feed efficiency of 0.05 units on a "deads out" basis in cattle fed 48 mg/kg when compared with those fed 33 mg/kg. In some herds, no additional improvement in feed efficiency was shown from feeding monensin at levels greater than 33 mg/kg. Decisions on the appropriate dose of monensin should be made in consultation with your veterinarian.

2. Feed labels must state one specific drug level.

Option 2: Feeding program approved with the use of Monensin Premix.
  1. Introductory period of 28 days:
    11 mg/kg (0.0011%) of monensin in the complete diet.
  2. Remainder of feeding period to market weight:
    33 mg/kg (0.0033%) of monensin in the complete diet

Note:

Complete diet refers to the complete feed plus the roughage (i.e., the total diet) and must be corrected to a 100% dry matter basis.

Directions for use:

At a level in supplements, premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Thoroughly mix the supplements and premixes in the total daily diet or in complete feed (grain portion of the ration) before use. Do not feed undiluted.

Medicated supplements and premixes fed as a percentage (%) of total diet dry matter:

Mixing medicated supplements or premixes as a percentage (%) of total diet dry matter is recommended. The following calculation can be used to assist in determining the amount of monensin required per kg of supplement/premix dry matter to meet the approved level of drug in the total diet dry matter:

mg monensin/kg supplement or premix dry matter = [approved drug level (mg/kg total diet dry matter) / (% inclusion of supplement or premix in diet on a 100% dry matter basis)] x 100

Medicated supplements and premixes fed as a fixed amount on a per head per day basis:

It may sometimes be preferable to mix the medicated supplement/premix in the complete feed or total diet as a fixed amount on a per head per day basis. The approved levels of monensin must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter (DM) intake.

Medicated complete feeds:

Medicated complete feeds are often fed separately from the forage part of the ration as a fixed amount on a per head per day basis. The approved levels of monensin must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter (DM) intake.

Note:

All monensin premixes are approved to be used in the following thixotropic liquid supplement:

  1. Promolas Liquid Supplement Suspension (Westway Feed Products).

Warning:

  1. Do not supplement monensin from other sources (e.g., other feedstuffs containing monensin or slow release devices containing monensin).
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Do not exceed recommended levels as reduced average daily gains may result.
  2. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
  3. Feed only to beef cattle (steers and heifers) intended for slaughter and maintained under confinement.
  4. May be used in feeds containing the following pellet-binding agents: bentonite (2%), attapulgite (2%), kaolin (2.5%), lignin sulfonate (4%), carboxymethylcellulose (0.1%), or Agri-Colloid. (Required on premix and supplement labels only.)
  5. Do not use thixotropic supplements after eight weeks of storage (Westway Feed Products) (Required on thixotropic liquid supplement labels only.)

Claim 4: As an aid in the prevention of coccidiosis caused by Eimeria bovis and Eimeria zuernii in cattle.

Note:

Coccidiosis occurs sporadically in first lactation dairy heifers, but is not considered a significant disease in mature dairy cows.

Level of Drug:

22 mg/kg (0.0022%) of monensin in the complete diet.

Note:

Complete diet refers to the complete feed plus the roughage (i.e., the total diet) and must be corrected to a 100% dry matter basis.

Directions for use:

At a level in supplements, premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied. Thoroughly mix supplements and premixes in the total daily diet or in complete feed (grain portion of the ration) before use.

Do not feed undiluted.

Medicated supplements and premixes fed as a percentage (%) of total diet dry matter:

Mixing medicated supplements or premixes as a percentage (%) of total diet dry matter is recommended. The following calculation can be used to assist in determining the amount of monensin required per kg of supplement/premix dry matter to meet the approved level of drug in the total diet dry matter:

mg monensin/kg supplement or premix dry matter = [approved drug level (mg/kg total diet dry matter) / (% inclusion of supplement or premix in the total diet on a 100% dry matter basis)] x 100

Medicated supplements and premixes fed as a fixed amount on a per head per day basis:

It may sometimes be preferable to mix the medicated supplement/premix in the complete feed or total diet as a fixed amount on a per head per day basis. The approved levels of monensin must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (% of body weight) x approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter (DM) intake.

Medicated complete feeds:

Medicated complete feeds are often fed separately from the forage part of the ration as a fixed amount on a per head per day basis. The approved levels of monensin must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter (DM) intake.

Note:

All monensin premixes are approved to be used in the following thixotropic liquid supplement:

  1. Promolas Liquid Supplement Suspension (Westway Feed Products).

Warning:

  1. Do not supplement monensin from other sources (e.g., other feedstuffs containing monensin or slow release devices containing monensin).
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Do not exceed recommended levels as reduced average daily gains may result.
  2. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
  3. Do not use monensin – medicated feed for the treatment of outbreaks of coccidiosis.
  4. May be used in feeds containing the following pellet-binding agents: bentonite (2%), attapulgite (2%), kaolin (2.5%), lignin sulfonate (4%), carboxymethylcellulose (0.1%), or Agri-Colloid. (Required on premix and supplement labels only.)
  5. Do not use thixotropic supplements after eight weeks of storage. (Westway Feed Products), (Required on thixotropic liquid supplement labels only.)

Claim 5: For increased rate of weight gain in growing cattle on pasture (slaughter, stocker and feeder cattle, and beef and dairy replacement heifers) of greater than 180 kg (400 lb) body weight.

Level of Drug:

200 mg of monensin per head per day.

Directions:

Hand feed continuously a minimum of 0.5 kg of medicated supplement per head per day, to supply 200 mg of monensin per head per day. The medicated supplement must be hand fed from the beginning to the end of the pasture season.

Note:

Medicated thixotropic liquid supplements should not be used for hand feeding cattle on cattle on pasture.

Warning:

  1. Do not supplement monensin from other sources (e.g., other feed stuffs containing monensin or slow release devices containing monensin).
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Do not exceed recommended levels as reduced average daily gains may result.
  2. Do not allow dogs, horses or other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
  3. Do not use monensin-medicated feed for the treatment of outbreaks of coccidiosis.
  4. May be used in feeds containing the following pellet-binding agents: bentonite (2%), attapulgite (2%), kaolin (2.5%), lignin sulfonate (4%), carboxymethylcellulose (0.1%), or Agri-Colloid. (Required on premix and supplement labels only.)

Claim 6: For reduction of milk fat percentage in lactating dairy cows.

Note:

The expected efficacy of this product for the reduction of milk fat percentage may be affected by dietary factors. Reduced efficacy may be expected with diets higher in fibre or lower in unsaturated oils.

Level of Drug:

16 mg/kg to 24 mg/kg (0.0016% to 0.0024%) of monensin in the complete diet.

Note:
  1. Feed labels must state one specific drug level.
  2. Complete diet refers to the complete feed plus the roughage (i.e., the total diet) and must be corrected to a 100% dry matter basis.
  3. Consult your veterinarian and/or nutritionist for additional information regarding the use of monensin in lactating dairy cattle.

Directions:

At a level in supplements, premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Thoroughly mix supplements and premixes in the total daily diet or in the complete feed (grain portion of the ration) before use. Do not feed undiluted.

Medicated supplements and premixes fed as a percentage (%) of total diet dry matter:

Mixing medicated supplements or premixes as a percentage (%) of total diet dry matter is recommended. The following calculation can be used to assist in determining the amount of monensin required per kg of supplement/premix dry matter to meet the approved level of drug in the total diet dry matter:

mg monensin/kg of supplement or premix dry matter = [approved drug level (mg/kg total diet dry matter) / (% inclusion of supplement or premix in the total diet on a 100% dry matter basis)] x 100

Medicated supplements and premixes fed as a fixed amount on a per head per day basis:

It may sometimes be preferable to mix the medicated supplement/premix in the complete feed or total diet as a fixed amount on a per head per day basis. The approved levels of monensin must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (% of body weight) x approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter (DM) intake.

Medicated complete feeds:

Medicated complete feeds are often fed separately from the forage part of the ration as a fixed amount on a per head per day basis. The approved levels of monensin must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter (DM) intake.

Note:

All monensin premixes are approved to be used in the following thixotropic liquid supplement:

  1. Promolas Liquid Supplement Suspension (Westway Feed Products).

Warning:

  1. Do not supplement more than 16 mg of monensin per kg of complete diet to dairy cows in herds administered slow release devices containing monensin.
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
  2. May be used in feeds containing the following pellet-binding agents: bentonite (2%), attapulgite (2%), kaolin (2.5%), lignin sulfonate (4%), carboxymethylcellulose (0.1%), or Agri-Colloid. (Required on premix and supplement labels only.)
  3. Do not use thixotropic supplements after eight weeks of storage. (Westway Feed Products) (Required on thixotropic liquid supplement labels only.)
  4. The 24 mg/kg (or 24 g/tonne of complete diet) monensin treatment in primiparous cows may result in the increased incidence of udder edema and increased number of inseminations per full term conception.
  5. The continuous use of monensin in dairy cows may be associated with increased rates of twinning and stillbirths, and heavier birth weights for heifer calves.

Claim 7: For minimizing loss of body condition during lactation in dairy cows.

Level of Drug:

mg/kg to 24 mg/kg (0.0008% to 0.0024%) of monensin in the complete diet.

Note:
  1. Feed labels must state one specific drug level.
  2. Complete diet refers to the complete feed plus the roughage (i.e., the total diet) and must be corrected to a 100% dry matter basis.
  3. Consult your veterinarian and/or nutritionist for additional information regarding the use of monensin in lactating dairy cattle.

Directions:

At a level in supplements, premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Thoroughly mix supplements and premixes in the total daily diet or in complete feed (grain portion of the ration) before use. Feed continuously during the dry and lactating periods. Do not feed undiluted.

Medicated supplements and premixes fed as a percentage (%) of total diet dry matter:

Mixing medicated supplements or premixes a percentage (%) of total diet dry matter is recommended. The following calculation can be used to assist in determining the amount of monensin required per kg of supplement/premix dry matter to meet the approved level of drug in the total diet dry matter:

mg monensin/kg of supplement or premix dry matter = [approved drug level (mg/kg total diet dry matter) / (% inclusion of supplement or premix in the total diet on a 100% dry matter basis)] x 100

Medicated supplements and premixes fed as a fixed amount on a per head per day basis:

It may sometimes be preferable to mix the medicated supplement/premix in the complete feed or total diet as a fixed amount on a per head per day basis. The approved levels of monensin must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (% of body weight) x approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter (DM) intake.

Medicated complete feeds:

Medicated complete feeds are often often fed separately from the forage part of the ration as a fixed amount on a per head per day basis. The approved levels of monensin must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg total diet dry matter)

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter (DM) intake.

Note:

All monensin premixes are approved to be used in the following thixotropic liquid supplement:

  1. Promolas Liquid Supplement Suspension (Westway Feed Products)

Warning:

  1. Do not supplement more than 16 mg of monensin per kg of complete diet to dairy cows in herds administered slow release devices containing monensin.
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
  2. May be used in feeds containing the following pellet-binding agents: bentonite (2%), attapulgite (2%), kaolin (2.5%), lignin sulfonate (4%), carboxymethylcellulose (0.1%), or Agri-Colloid. (Required on premix and supplement labels only.)
  3. Do not use thixotropic supplements after eight weeks of storage. (Westway Feed Products) (Required on thixotropic liquid supplement labels only.)
  4. The 24 mg/kg (or 24 g/tonne of complete diet) monensin treatment in primiparous cows may result in the increased incidence of udder edema and increased number of inseminations per full term conception.
  5. The continuous use of monensin in dairy cows may be associated with increased rates of twinning and stillbirths, and heavier birth weights for heifer calves.

Claim 8: For improving feed efficiency of milk protein production in lactating dairy cows.

Level of Drug:

16 mg/kg to 24 mg/kg (0.0016% to 0.0024%) of monensin in the complete diet.

Note:
  1. Feed labels must state one specific drug level.
  2. Complete diet refers to the complete feed plus the roughage (i.e., the total diet) and must be corrected to a 100% dry matter basis.
  3. Consult your veterinarian and/or nutritionist for additional information regarding the use of monensin in lactating dairy cattle.

Directions:

At a level in supplements, premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Thoroughly mix supplements and premixes in the total daily diet or in complete feed (grain portion of the ration) before use. Do not feed undiluted.

Medicated supplements and premixes fed as a percentage (%) of total diet dry matter:

Mixing medicated supplements or premixes as a percentage (%) of total diet dry matter is recommended. The following calculation can be used to assist in determining the amount of monensin required per kg of supplement/premix dry matter to meet the approved level of drug in the total diet dry matter:

mg monensin/kg of supplement or premix dry matter = [approved drug level (mg/kg total diet dry matter) / (% inclusion of or premix in the total diet on a 100% dry matter basis)] x 100

Medicated supplements and premixes fed as a fixed amount on a per head per day basis:

It may sometimes be preferable to mix the medicated supplement/premix in the complete feed or total diet as a fixed amount on a per head per day basis. The approved levels of monensin must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (% of body weight) x approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter (DM) intake.

Medicated complete feeds:

Medicated complete feeds are often fed separately from the forage part of the ration as a fixed amount on a per head per day basis. The approved levels of monensin must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter (DM) intake.

Note:

All monensin premixes are approved to be used in the following thixotropic liquid supplement:

  1. Promolas Liquid Supplement Suspension (Westway Feed Products)

Warning:

  1. Do not supplement more than 16 mg of monensin per kg of complete diet to dairy cows in herds administered slow release devices containing monensin.
  2. Keep out of reach of children. (Required on premix and supplement labels only.)

Caution:

  1. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
  2. May be used in feeds containing the following pellet-binding agents: bentonite (2%), attapulgite (2%), kaolin (2.5%), lignin sulfonate (4%), carboxymethylcellulose (0.1%), or Agri-Colloid. (Required on premix and supplement labels only.)
  3. Do not use thixotropic supplements after eight weeks of storage. (Westway Feed Products), (Required on thixotropic liquid supplement labels only.)
  4. The 24 mg/kg (or 24 g/tonne of complete diet) monensin treatment in primiparous cows may result in the increased incidence of udder edema and increased number of inseminations per full term conception.
  5. The continuous use of monensin in dairy cows may be associated with increased rates of twinning and stillbirths, and heavier birth weights for heifer calves.

Accepted Compatibilities

Monensin sodium is compatible in single combination with any of the following drugs. For details refer to the MIB as indicated.
MIB #Medicated ingredients For use in feeds for
10.11 Virginiamycin broiler chickens
10.12 Bambermycins broiler chickens
43 Monensin sodium (Claim 3 option 1a and option 2) is compatible with:
Tylosin Phosphate (Claim 4)
feedlot beef cattle
46 Melengestrol acetate feedlot beef heifers
48 Bacitracin methylene disalicylate broiler chickens
80 Tilmicosin (Claim 3) feedlot beef cattle
Monensin sodium (claim 3 option 1b) is compatible with multiple drugs in the following combination. For details refer to the MIB as indicated.
MIB #Medicated ingredients For use in feeds for

43

46

Tylosin Phosphate from Tylan and Tylosin Premixes (Claim 4);
AND

Melengestrol acetate

feedlot beef heifers
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