Ractopamine Hydrochloride - MIB #82

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Date Revised: 2016-02

Approved Brands

  1. Paylean 20 contains ractopamine hydrochloride at 20 g/kg (Elanco).
  2. Optaflexx 100 contains ractopamine hydrochloride at 100 g/kg (Elanco).
  3. Engain 20 contains ractopamine hydrochloride at 20 g/kg (Zoetis Canada Inc.).
  4. Actogain 100 contains ractopamine hydrochloride at 100 g/kg (Zoetis Canada Inc.).
  5. Ractopamine 100 contains ractopamine hydrochloride at 100 g/kg (Bio Agri Mix LP).

Approved for use

In meal or pellet feed for finishing barrows and gilts, confined finishing cattle and finishing heavy turkeys (toms and hens) only.

Optaflexx 100 is approved for use in liquid feed supplements for confined finishing cattle.

Approved Claims

For finishing barrows and gilts - Claims 1 and 2.
For confined finishing cattle greater than 400 kg body weight - Claims 3 and 4.
For finishing heavy tom turkeys in their last 14 days prior to slaughter - Claim 5.
For finishing heavy hen turkeys in their last 7 to 14 days prior to slaughter - Claim 6.

Claim 1, 2, 5 and 6 are approved with the use of Paylean 20 and Engain 20
Claim 3 and 4 are approved with the use of Optaflexx 100, Actogain 100 and Ractopamine 100.

Claim 1: For increased carcass leanness, increased dressing percent, improved rate of weight gain and improved feed efficiency in finishing barrows and gilts.

Level of Drug:

10 mg/kg (0.001%) of ractopamine hydrochloride in the complete feed.

Directions:

Feed continuously as sole ration to finishing barrows and gilts, that are a minimum 70 kg starting body weight for no longer than six (6) weeks.

Note:

To obtain the performance benefits of ractopamine hydrochloride, diets should contain a minimum of 16% crude protein, or its equivalent obtained by amino acid (0.85-0.95% lysine) fortification. Dietary specifications should be determined in consultation with a recognized swine nutritionist (Required on premix and supplement labels only).

Warning:

  1. Ractopamine hydrochloride is beta-adrenergic agonist. Individuals with cardiovascular disease should exercise special caution to avoid exposure to this medicated feed (Required on premix and supplement labels only).
  2. Keep out of reach of children (Required on premix and supplement labels only).

Caution:

  1. Do not feed to male or female swine intended for reproduction including pregnant swine and swine in lactation.
  2. Do not feed to pigs intended to be retained for breeding.
  3. Do not feed medicated feeds containing ractopamine hydrochloride for more than six (6) weeks.
  4. The use of ractopamine hydrochloride in pigs finishing over 132  kg body weight has not been studied.
  5. Pigs fed ractopamine hydrochloride may be at increased risk for exhibiting the fatigued or downer pig syndrome particularly when marketed at high body weights. Pig handling methods to reduce the incidence of fatigued or downer pigs should be thoroughly evaluated prior to initiating the use of this medicated feed.

Claim 2: For improved rate of weight gain and feed efficiency in finishing barrows and gilts.

Level of Drug:

mg/kg - 10 mg/kg (0.0005% - 0.001%) of ractopamine hydrochloride in the complete feed.

Directions:

Feed continuously as sole ration to finishing barrows and gilts, that are a minimum 70 kg starting body weight, for no longer than six (6) weeks.

Note:

To obtain the performance benefits of ractopamine hydrochloride, diets must contain a minimum of 16% crude protein, or its equivalent obtained by amino acid (0.85-0.95% lysine) fortification. Dietary specifications should be determined in consultation with a recognized swine nutritionist (Required on premix and supplement labels only).

Warning:

  1. Ractopamine hydrochloride is beta-adrenergic agonist. Individuals with cardiovascular disease should exercise special caution to avoid exposure to this medicated feed (Required on premix and supplement labels only).
  2. Keep out of reach of children (Required on premix and supplement labels only).

Caution:

  1. Do not feed to male or female swine intended for reproduction including pregnant swine and swine in lactation.
  2. Do not feed to pigs intended to be retained for breeding.
  3. Do not feed medicated feeds containing ractopamine hydrochloride for more than six (6) weeks.
  4. The use of ractopamine hydrochloride in pigs finishing over 132 kg body weight has not been studied.
  5. Pigs fed ractopamine hydrochloride may be at increased risk for exhibiting the fatigued or downer pig syndrome particularly when marketed at high body weights. Pig handling methods to reduce the incidence of fatigued or downer pigs should be thoroughly evaluated prior to initiating the use of this medicated feed.

Claim 3: For increased rate of weight gain and improved feed efficiency in cattle greater than 400 kg body weight fed in confinement during the last 28 to 42 days prior to slaughter.

Level of Drug:

10 mg/kg - 30 mg/kg (0.001% - 0.003%) of ractopamine hydrochloride in the total diet.

Note:

  1. Feed labels must state one specific drug level.
  2. Total diet refers to the complete feed plus the roughage and must be corrected to a 100% dry matter basis.

Directions:

At a level in supplements (dry or liquid), premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Note: Liquid medicated supplements are approved with the use of the Optaflexx 100.

Feed continuously as sole ration to finishing cattle greater than 400 kg body weight for 28 to 42 days prior to slaughter.

Thoroughly mix in the total daily diet before use.

Do not feed undiluted.

Medicated supplement or premix fed as a % of total diet dry matter:

Mixing medicated supplements or premixes as a % of total diet dry matter is ideal. The following calculation can be used to assist in determining the amount of ractopamine hydrochloride required per kg of supplement or premix to meet the approved level of drug in the total diet dry matter:

mg ractopamine hydrochloride/kg dry supplement or premix =

approved drug level (mg/kg total diet dry matter) X 100 ÷
% inclusion of supplement or premix into diet on a 100% dry matter basis

Medicated supplement or premix fed as a fixed amount/head/day:

It may sometimes be preferable to mix the medicated supplement or premix in the total diet as a fixed amount/head/day. The approved levels of ractopamine hydrochloride must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg/head/day = weight of animal (kg) X dry matter intake (% of body weight) X approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Warning:

  1. Do not feed to calves to be processed for veal.
  2. Ractopamine hydrochloride is a beta-adrenergic agonist. Individuals with cardiovascular disease should exercise special caution to avoid exposure to this medicated feed (Required on premix and supplement labels only).
  3. Keep out of reach of children (Required on premix and supplement labels only).
  4. Do not feed to lactating dairy cattle.

Caution:

  1. Do not use this medicated feed after nine (9) weeks of storage (Required on liquid supplement labels only).
  2. This medicated feed must be maintained in a pH range of 4.5 - 7.5 (Required on liquid supplement labels only).

Claim 4: For increased carcass leanness in cattle greater than 400 kg body weight fed in confinement during the last 28 to 42 days prior to slaughter.

Level of Drug:

20 mg/kg - 30 mg/kg (0.002% - 0.003%) of ractopamine hydrochloride in the total diet.

Note:

  1. Feed labels must state one specific drug level.
  2. Total diet refers to the complete feed plus the roughage and must be corrected to a 100% dry matter basis.

Directions:

At a level in supplements (dry or liquid), premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Note: Liquid medicated supplements are approved with the use of the Optaflexx 100.

Feed continuously as sole ration to finishing cattle greater than 400 kg body weight for 28 to 42 days prior to slaughter.

Thoroughly mix in the total daily diet before use.

Do not feed undiluted.

Medicated supplement or premix fed as a % of total diet dry matter:

Mixing medicated supplements or premixes as a % of total diet dry matter is ideal. The following calculation can be used to assist in determining the amount of ractopamine hydrochloride required per kg of supplement or premix to meet the approved level of drug in the total diet dry matter:

mg ractopamine hydrochloride/kg dry supplement or premix =

approved drug level (mg/kg total diet dry matter) X 100 ÷
% inclusion of supplement or premix into diet on a 100% dry matter basis

Medicated supplement or premix fed as a fixed amount/head/day:

It may sometimes be preferable to mix the medicated supplement or premix in the total diet as a fixed amount/head/day. The approved levels of ractopamine hydrochloride must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg/head/day = weight of animal (kg) X dry matter intake (% of body weight) X approved drug level (mg/kg total diet dry matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Warning:

  1. Do not feed to calves to be processed for veal.
  2. Ractopamine hydrochloride is a beta-adrenergic agonist. Individuals with cardiovascular disease should exercise special caution to avoid exposure to this medicated feed (Required on premix and supplement labels only).
  3. Keep out of reach of children (Required on premix and supplement labels only).
  4. Do not feed to lactating dairy cattle.

Caution:

  1. Do not use this medicated feed after nine (9) weeks of storage (Required on liquid supplement labels only).
  2. This medicated feed must be maintained in a pH range of 4.5 - 7.5 (Required on liquid supplement labels only).

Claim 5: For increased rate of weight gain and improved feed efficiency in finishing heavy tom turkeys when fed for the last 14 days prior to slaughter.

Level of Drug:

mg/kg - 9 mg/kg (0.0005% - 0.0009%) of ractopamine hydrochloride in the complete feed.

Directions:

Feed continuously as sole ration to finishing heavy tom turkeys for the last 14 days prior to slaughter.

Note:

Turkeys growing at or near their genetic potential may not be able to respond to ractopamine hydrochloride unless sufficient lysine intake is achieved. Dietary specifications should be determined in consultation with a recognized poultry nutritionist (Required on premix and supplement labels only).

Warning:

  1. Ractopamine hydrochloride is a beta-adrenergic agonist. Individuals with cardiovascular disease should exercise special caution to avoid exposure to this medicated feed (Required on premix and supplement labels only).
  2. Keep out of reach of children (Required on premix and supplement labels only).

Caution:

  1. Do not feed to turkeys intended for breeding.
  2. Feeding ractopamine hydrochloride to tom turkeys during periods of excessive heat can result in increased mortality.

    Note: (Required on the label):
    "Proper handling techniques should be used to avoid an increased rate of injuries and mortality associated with transportation."

Claim 6: For increased rate of weight gain and improved feed efficiency in finishing heavy hen turkeys when fed for the last 7 to 14 days prior to slaughter.

Level of Drug:

mg/kg - 9 mg/kg (0.0005% - 0.0009%) of ractopamine hydrochloride in the complete feed.

Directions:

Feed continuously as sole ration to finishing heavy hen turkeys for the last 7 to 14 days prior to slaughter.

Note:

Turkeys growing at or near their genetic potential may not be able to respond to ractopamine hydrochloride unless sufficient lysine intake is achieved. Dietary specifications should be determined in consultation with a recognized poultry nutritionist (Required on premix and supplement labels only).

Warning:

  1. Ractopamine hydrochloride is a beta-adrenergic agonist. Individuals with cardiovascular disease should exercise special caution to avoid exposure to this medicated feed (Required on premix and supplement labels only).
  2. Keep out of reach of children (Required on premix and supplement labels only).

Caution:

  1. Do not feed to turkeys intended for breeding.

    Note: (Required on the label):
    "Proper handling techniques should be used to avoid an increased rate of injuries and mortality associated with transportation."

Accepted Compatibilities

Nil

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