Canadian Food Inspection Agency
www.inspection.gc.ca
Common menu bar links
Institutional links
-
About the CFIA
-
Subjects
-
Proactive Disclosure
Send this page by
emailOXYTETRACYCLINE HYDROCHLORIDE - MIB#35
Date Revised: 2006-09
Approved Brands
- TERRAMYCIN-50 contains oxytetracycline hydrochloride at 110 g/kg (Pfizer Canada Inc.)
- TERRAMYCIN-100 contains oxytetracycline hydrochloride at 220 g/kg (Pfizer Canada Inc.)
- TERRAMYCIN-200 contains oxytetracycline hydrochloride at 440 g/kg (Pfizer Canada Inc.)
- OXYSOL 110 contains oxytetracycline hydrochloride at 110 g/kg (Vétoquinol N.-A. Inc.)
- OXYSOL 220 contains oxytetracycline hydrochloride at 220 g/kg (Vétoquinol N.-A. Inc.)
- OXYSOL 440 contains oxytetracycline hydrochloride at 440 g/kg (Vétoquinol N.-A. Inc.)
- OXYTETRACYCLINE 50 PREMIX contains oxytetracycline hydrochloride at 110 g/kg (Bio AgriMix)
- OXYTETRACYCLINE 100 PREMIX contains oxytetracycline hydrochloride at 220 g/kg (Bio AgriMix)
- OXYTETRACYCLINE 200 PREMIX contains oxytetracycline hydrochloride at 440 g/kg (Bio AgriMix)
- OXY - 110 contains oxytetracycline hydrochloride at 110 g/kg (Medprodex Inc.)
- OXY - 220 contains oxytetracycline hydrochloride at 220 g/kg (Medprodex Inc.)
- OXY - 440 contains oxytetracycline hydrochloride at 440 g/kg (Medprodex Inc.)
Approved for use
In meal or pellet feed for broiler, replacement, and laying chickens; turkeys; lambs; swine; beef cattle; calves and calf milk replacers.
Approved claims
For broiler chickens - Claim 1, 2, 3, 4, 5, 6, 7, 8
For laying chickens - Claim 9, 10, 11, 12, 13, 14
For replacement chickens - Claim 15, 16, 17, 18, 19, 20, 21
For turkeys - Claim 22, 23, 24, 25, 26, 27, 28, 29, 30
For lambs - Claim 31, 32
For swine - Claim 33, 34, 35, 36, 37
For beef cattle - Claim 38
For calves - Claim 39
For calves (milk replacers) - Claim 40
Claim 1: As an aid in stimulating appetite and maintaining weight gains in broiler chickens during periods of stress caused by moving, debeaking, chilling, vaccination, extreme temperatures.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 2: As an aid in stimulating appetite and maintaining weight gains in broiler chickens when birds are expected to be exposed to mild attacks of Chronic Respiratory Disease (CRD) and Non-Specific Enteritis.
Level of Drug:
55 mg/kg (0.0055%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration for as long as birds are expected to be exposed to infection.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 3: As an aid in stimulating appetite and maintaining weight gains, and feed efficiency in broiler chickens in the presence of CRD.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 4: As an aid in stimulating appetite, maintaining weight gains, and feed efficiency in broiler chickens in the presence of CRD and while under stress caused by moving, debeaking, vaccination or extreme temperature changes.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 5: As an aid in stimulating appetite, and maintaining weight gains in broiler chickens in the presence of CRD and as an aid in stimulating and maintaining weight gains during periods of stress.
Level of Drug:
220 mg/kg (0.022%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 6 : As an aid in stimulating appetite and maintaining weight gains in broiler chickens in the presence of Non-Specific Enteritis.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of symptoms for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 7: As an aid in stimulating appetite and maintaining weight gains in broiler chickens during periods of stress caused by moving, debeaking, vaccination or extreme temperature change.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration. In case of vaccination feed for 8-10 days immediately following vaccination. For other stress conditions, feed for at least five days.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 8: As an aid in increasing oxytetracycline levels in the blood of broiler chickens. The calcium level of this feed has been reduced to ...%.
Level of Drug:
220 mg/kg (0.022%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration to broiler chickens.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Note:
- As an aid in increasing oxytetracycline levels in the blood, dietary calcium may be reduced to not less than 0.6%, and not more than 0.8%. Added calcium should be derived from calcium sulfate. Feed phosphorus levels should not be less than 0.55%.
- Do not feed to laying hens and turkeys.
- Claim 8 is to be used in conjunction with another claim such as claim 6.
Claim 9: As an aid in stimulating appetite and maintaining weight gains in laying chickens during periods of stress caused by moving, debeaking, chilling, vaccination, extreme temperatures and in increasing egg production, hatchability and feed efficiency following drops in these caused by the above mentioned changes.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 10: As an aid in stimulating appetite and maintaining weight gains in laying chickens when birds are expected to be exposed to mild attacks of CRD and Non-Specific Enteritis.
Level of Drug:
55 mg/kg (0.0055%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration for as long as birds are expected to be exposed to infection.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 11: As an aid in stimulating appetite and maintaining weight gains, egg production, hatchability, eggshell quality and feed efficiency in laying chickens in the presence of CRD and increasing egg production, hatchability and feed efficiency following drops in these caused by CRD.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 12: As an aid in stimulating appetite, maintaining weight gains, egg production, hatchability, eggshell quality and feed efficiency in laying chickens in the presence of CRD and while under stress caused by moving, debeaking, vaccination or extreme temperature changes.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 13: As an aid in stimulating appetite, and maintaining weight gains in laying chickens in the presence of CRD and as an aid in stimulating and maintaining weight gains during periods of stress.
Level of Drug:
220 mg/kg (0.022%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 14: As an aid in stimulating appetite and maintaining weight gains in laying chickens in the presence of Non-Specific Enteritis.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of symptoms for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 15: As an aid in stimulating appetite and maintaining weight gains in replacement chickens during periods of stress caused by moving, debeaking, chilling, vaccination, extreme temperatures and in increasing feed efficiency following drops in these caused by the above mentioned changes.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 16: As an aid in stimulating appetite and maintaining weight gains in replacement chickens when birds are expected to be exposed to mild attacks of CRD and Non-Specific Enteritis.
Level of Drug:
55 mg/kg (0.0055%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration for as long as birds are expected to be exposed to infection.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 17: As an aid in stimulating appetite and maintaining weight gains, and feed efficiency in replacement chickens in the presence of CRD.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 18: As an aid in stimulating appetite, maintaining weight gains, and feed efficiency in replacement chickens in the presence of CRD and while under stress caused by moving, debeaking, vaccination or extreme temperature changes.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 19: As an aid in stimulating appetite, and maintaining weight gains in replacement chickens in the presence of CRD and as an aid in stimulating and maintaining weight gains during periods of stress.
Level of Drug:
220 mg/kg (0.022%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 20: As an aid in stimulating appetite and maintaining weight gains in replacement chickens in the presence of Non-Specific Enteritis.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of symptoms for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 21: As an aid in increasing oxytetracycline levels in the blood of replacement chickens. The calcium level of this feed has been reduced to ...%.
Level of Drug:
220 mg/kg (0.022%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration to broiler chickens.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Note:
- As an aid in increasing oxytetracycline levels in the blood, dietary calcium may be reduced to not less than 0.6%, not more than 0.8%. Added calcium should be derived from calcium sulfate. Feed phosphorus levels should not be less than 0.55%.
- Do not feed to laying hens and turkeys.
- Claim 21 is to be used in conjunction with another claim such as claim 20.
Claim 22: As an aid in stimulating appetite and maintaining weight gains in turkeys during periods of stress caused by moving, debeaking, chilling, vaccination, extreme temperatures and in increasing egg production, hatchability and feed efficiency following drops in these caused by the above mentioned changes.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 23: As an aid in stimulating appetite and maintaining weight gains in turkeys when birds are expected to be exposed to mild attacks of CRD and Non-Specific Enteritis.
Level of Drug:
55 mg/kg (0.0055%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration for as long as birds are expected to be exposed to infection.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.
Claim 24: As an aid in stimulating appetite and maintaining weight gains, egg production, hatchability, eggshell quality and feed efficiency in turkeys in the presence of CRD and increasing egg production, hatchability and feed efficiency following drops in these caused by CRD.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 25: As an aid in stimulating appetite, maintaining weight gains, egg production, hatchability, eggshell quality and feed efficiency in turkeys in the presence of CRD and while under stress caused by moving, debeaking, vaccination or extreme temperature changes.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 26: As an aid in stimulating appetite, and maintaining weight gains in turkeys in the presence of CRD and as an aid in stimulating and maintaining weight gains during periods of stress.
Level of Drug:
220 mg/kg (0.022%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of the disease for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 27: As an aid in stimulating appetite and maintaining weight gains in turkeys in the presence of Non-Specific Enteritis.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration from the onset of symptoms for at least one month or until a few days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 28: As an aid in stimulating appetite and maintaining weight gains in turkeys during periods of stress caused by moving, debeaking, vaccination or extreme temperature change.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration. In case of vaccination feed for 8-10 days immediately following vaccination. For other stress conditions, feed for at least five days.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 29: As an aid in the prevention of Synovitis and Infectious Sinusitis in turkeys.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed as the sole ration for as long as birds are expected to be exposed to infection.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 30: As an aid in the treatment of Synovitis in turkeys.
Level of Drug:
220 mg/kg (0.022%) of complete feed.
Directions:
Feed this medicated feed as the sole ration when symptoms appear and continue until at least 2 weeks after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated birds are slaughtered for use in food.
Claim 31: As an aid in the reduction of Bacterial Diarrhoea in creep-fed suckling lambs.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole creep feed during the suckling period.
Warning:
- Discontinue the use of this medicated feed at least 4 days before treated lambs are slaughtered for use in food.
Claim 32: As an aid in the reduction of losses due to Enterotoxemia in feed-lot lambs.
Level of Drug:
22 mg/kg (0.0022%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration while lambs are in the feed-lot.
Warning:
- Discontinue the use of this medicated feed at least 4 days before treated lambs are slaughtered for use in food.
Claim 33: As an aid in prevention of Bacterial Enteritis (Scours) (Bacterial Diarrhoea) in pigs.
Level of Drug:
55 mg/kg (0.0055%) of complete feed.
Directions:
Feed this medicated feed as the sole ration during the period of early growth up to 27-31 kg.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.
Note:
- Pre-Starters and feeds to be fed up to and including 6 weeks of age are required to contain 0.022% of oxytetracycline hydrochloride.
Claim 34: As an aid in the treatment of Bacterial Enteritis (Scours) (Bacterial Diarrhoea) in pigs.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed continuously as the sole ration following the appearance of symptoms and until 3 days after symptoms disappear.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.
Note:
- When treatment claim is made, label must show this statement: Pigs off feed should be given individual treatment.
- Pre-Starters and feeds to be fed up to and including 6 weeks of age, are required to contain 0.022% of oxytetracycline hydrochloride.
Claim 35: As an aid in maintaining weight gains in the presence of Atrophic Rhinitis in swine.
Level of Drug:
55 mg/kg (0.0055%) of complete feed.
Directions:
Feed this medicated feed as the sole ration for as long as the symptoms of Atrophic Rhinitis persist.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.
Note:
- Label must show this statement: This medicated feed has no effect on the organism causing Atrophic Rhinitis.
- Do not use in Pre-starter feeds.
Claim 36: For stimulation of appetite and maintenance of weight gains during periods of stress caused by moving, vaccination, extreme temperature change and castration in pigs.
Level of Drug:
110 mg/kg (0.011%) of complete feed.
Directions:
Feed this medicated feed as the sole ration during periods of stress and until 10 days after the stress conditions have been eliminated.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated animals are slaughter for use in food.
Claim 37: As an aid in reducing the incidence of abortion in swine caused by Leptospirosis.
Level of Drug:
550 mg/kg (0.055%) of complete feed.
Directions:
When abortion in swine due to Leptospirosis has been diagnosed, feed this medicated feed at once as sole ration to pregnant and affected sows for a 2 week period.
Warning:
- Discontinue the use of this medicated feed at least 7 days before treated animals are slaughtered for use in food.
Note:
- Good sanitation procedures must be practised to prevent spread of infection.
Claim 38: As an aid in reducing the incidence of Bloat in young cattle on pasture and in feedlots.
Level of Drug:
Level of the drug in the complete feed is to be such that each animal will receive 75 mg per head per day.
Directions:
Feed this medicated feed continuously.
Warning:
Discontinue the use of this medicated feed at least 5 days before treated animals are slaughtered for use in food.
Note:
- Do not use in feeds for dairy cows.
Claim 39: As an aid in the prevention of Bacterial Diarrhoea in calves.
Level of Drug:
55 mg/kg (0.0055%) of complete feed.
Directions:
Feed this medicated feed continuously during period of early growth.
Warning:
Discontinue the use of this medicated feed at least 5 days before treated calves are slaughtered for use in food.
Claim 40: As an aid in the prevention of Bacterial Diarrhoea in calves.
Level of Drug:
55 mg/kg (0.0055%) of milk replacer powder.
Directions:
Feed this medicated feed continuously during periods of early growth.
Warning:
Discontinue the use of this medicated feed at least 5 days before treated calves are slaughtered for use in food.
Accepted Compatibilities
Oxytetracycline hydrochloride is compatible with the following drug/drug combinations. For details refer to the MIB as indicated.
| Number | Medicated ingredients | For use in feed for |
|---|---|---|
| 1. | Amprolium (MIB #27) | broiler chickens; replacement chickens; turkeys |
| 2. | Arsanilic acid (MIB #4) | broiler chickens; replacement chickens; turkeys; swine |
| 3. | Hygromycin B (MIB #20) | broiler chickens; replacement laying chickens; swine |
| 4. | 3-nitro-4-hydroxyphenylarsonic acid (MIB #21) | broiler chickens; replacement chickens; laying chickens; turkeys; swine |
| 5. | Zoalene (MIB #7) | broiler chickens; replacement chickens; turkeys |
