MONENSIN SODIUM - MIB #57

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Date Revised: 2008-02

Approved Brands

1. COBAN PREMIX contains monensin (as monensin sodium) at 200 g/kg (Elanco)
2. RUMENSIN PREMIX contains monensin (as monensin sodium) at 200 g/kg (Elanco)
3. MONENSIN PREMIX contains monensin (as monensin sodium) at 200 g/kg (Bio Agri Mix Ltd.)

Approved for use

In meal or pellet feed for broiler chickens, cattle and turkeys.
In thixotrope liquid supplements for cattle (RUMENSIN PREMIX and COBAN PREMIX only and must not be fed directly).

Approved claims

For broiler chickens - Claim 1
For turkeys - Claim 2
For beef cattle - Claim 3
For cattle - Claim 4
For pasture cattle - Claim 5
For lactating dairy cows - claims 6 and 8
For dry and lactating dairy cows - claim 7

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Claim 1: As an aid in the prevention of coccidiosis in broiler chickens caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. mitis, and E. maxima.

Level of Drug

99 mg/kg (0.0099%) of monensin activity in the complete feed.

Directions:

Feed this medicated feed as sole ration.

Warning:

1. Do not feed to replacement or laying chickens.

Caution:

1. Do not use this medicated feed for treatment of outbreaks of Coccidiosis.
2. Do not allow dogs, horses, other equines, or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
3. Poultry consuming monensin should not be treated with products containing tiamulin. Severe growth depression may occur.
4. May be used in feeds containing the pellet binding agents Bentonite (2%), Attapulgite (2%), Kaolin (2.5%), Lignin Sulfonate (4%), Carboxymethyl cellulose (0.1%), or Agri-Colloid (Premix and Supplement labels only).

Claim 2: As an aid in the prevention of Coccidiosis in growing turkeys caused by Eimeria adenoeides, E. meleagrimitis, and E. gallapavonis.

Level of Drug:

99 mg/kg (0.0099%) of monensin activity, in the complete feed.

Directions:

1. Feed this medicated feed as the sole ration to growing turkeys of less than 10 weeks of age. (medicated feeds containing MONENSIN PREMIX only).
2. Feed this medicated feed as the sole ration to growing turkeys. (Medicated feeds containing COBAN or RUMENSIN PREMIXES, only).

Warning:

1. Do not feed to replacement, laying or breeding turkeys.

Caution:

1. Do not use this medicated feed for treatment of outbreaks of Coccidiosis.
2. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestions of monensin by these species has been fatal.
3. Poultry consuming monensin should not be treated with products containing tiamulin. Severe growth depression may occur.
4. Do not feed to turkeys over 10 weeks of age (Medicated feeds containing MONENSIN PREMIX only).
5. Some species of turkey coccidia may be monensin tolerant.
6. May be used in feeds containing the pellet-binding agents Bentonite (2%), Attapulgite (2%), Kaolin (2.5%), Lignin Sulfonate (4%), Carboxymethyl cellulose (0.1%), or Agri-Colloid (Premix and supplement labels only).

Claim 3: For improved feed efficiency in beef cattle (steers and heifers) fed in confinement for slaughter.

Level of Drug:

Chose one of the feeding programs provided below:

Option 1:

Day 0 to market weight:
Monensin activity 33 mg/kg  (0.0033%) in the complete diet.

Option 2:

1. Introductory period of 28 days:
   monensin activity 11 mg/kg  (0.0011%) in the complete diet.
2. Remainder of feeding period to market weight:
   monensin activity 33 mg/kg  (0.0033%) in the complete diet

Note:

Complete diet refers to the complete feed plus the roughage and must be corrected to a 100% dry matter basis.

Directions for use:

At a level in supplements, premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Thoroughly mix the supplements and premixes in the total daily diet or in complete feed (grain portion of the ration) before use. Do not feed undiluted.

Medicated supplement/premix fed as a % of total diet dry matter:

Mixing medicated supplements or premixes as a % of total diet dry matter is ideal. The following calculation can be used to assist in determining the amount of monensin sodium required per kg of supplement/premix dry matter to meet the approved level of drug in the total diet dry matter;

mg monensin/kg supplement/premix dry matter = (approved drug level (mg/kg  total diet Dry Matter)) / (% inclusion of supplement/premix into diet on a 100% dry matter basis) x 100

Medicated supplement/premix fed as a fixed amount/head/day:

It may sometimes be preferable to mix the medicated supplement/premix in the complete feed or total diet as a fixed amount/head/day. The approved levels of monensin sodium must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg/head/day = weight of animal (kg) x dry matter intake (% of body weight) x approved drug level (mg/kg  total diet Dry Matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Medicated complete feeds:
Medicated complete feeds are often fed separately from the forage part of the ration on a fixed amount/head/day. The approved levels of monensin sodium must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg  total diet Dry Matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Note:

RUMENSIN PREMIX and COBAN PREMIX only can be used in the following thixotrope liquid supplements:

1. HCS, Nutrena Feeds, Cargill Limited;
2. Promolas Liquid Supplement Suspension, Westway Feed Products, a Division of Westway Holdings Canada Inc.

Warning:

1. Do not supplement monensin from other sources (e.g. other feedstuffs containing monensin or the Rumensin Controlled Release Capsule).

Caution:

1. Do not exceed recommended levels as reduced average daily gains may result.
2. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
3. Feed only to beef cattle (steers and heifers) intended for slaughter and maintained under confinement.
4. May be used in feeds containing the pellet-binding agents Bentonite (2%), Attapulgite (2%), Kaolin (2.5%), Lignin Sulfonate(4%), Carboxymethyl cellulose (0.1%), or Agri-Colloid. (Premix and supplement labels only).
5. Do not use thixotropic supplements after four weeks storage (Cargill thixotropic liquid supplement labels only).
6. Do not use thixotropic supplements after eight weeks storage (Westway Feed Products, A Division of Westway Holdings Canada Inc., thixotropic liquid supplement labels only).

Claim 4: As an aid in the prevention of Coccidiosis caused by Eimeria bovis and Eimeria zuernii in cattle.

Note:

Coccidiosis occurs sporadically in first lactation dairy heifers, but is not considered a significant disease in mature dairy cows.

Level of Drug:

Monensin activity 22 mg/kg  (0.0022%) in the complete diet.

Note:

Complete diet refers to the complete feed plus the roughage and must be corrected to a 100% dry matter basis.

Directions for use:

At a level in supplements, premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Thoroughly mix supplements and premixes in the total daily diet or in complete feed (grain portion of the ration) before use. Do not feed undiluted.

Medicated supplement/premix fed as a % of total diet dry matter:

Mixing medicated supplements or premixes as a % of total diet dry matter is ideal. The following calculation can be used to assist in determining the amount of monensin sodium required per kg of supplement/premix dry matter to meet the approved level of drug in the total diet dry matter;

mg monensin/kg supplement/premix dry matter = (approved drug level (mg/kg  total diet Dry Matter)) / (% inclusion of supplement/premix into diet on a 100% dry matter basis) x 100

Medicated supplement/premix fed as a fixed amount/ head/ day:

It may sometimes be preferable to mix the medicated supplement/premix in the complete feed or total diet as a fixed amount/head/day. The approved levels of monensin sodium must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg/head/day = weight of animal (kg) x dry matter intake (% of body weight) x approved drug level (mg/kg  total diet Dry Matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Medicated complete feeds:
Medicated complete feeds are often fed separately from the forage part of the ration on a fixed amount/head/day. The approved levels of monensin sodium must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg  total diet Dry Matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Note:

RUMENSIN PREMIX and COBAN PREMIX only can be used in the following thixotrope liquid supplements:

1. HCS, Nutrena Feeds, Cargill Limited;
2. Promolas Liquid Supplement Suspension, Westway Feed Products, a Division of Westway Holdings Canada Inc.

Warning:

1. Do not supplement monensin from other sources (e.g. other feedstuffs containing monensin or the Rumensin Controlled Release Capsule).

Caution:

1. Do not exceed recommended levels as reduced average daily gains may result.
2. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
3. Do not use monensin- medicated feed for the treatment of outbreaks of coccidiosis.
4. May be used in feeds containing the pellet-binding agents Bentonite (2%), Attapulgite (2%), Kaolin (2.5%), Lignin Sulfonate(4%), Carboxymethyl cellulose (0.1%), or Agri-Colloid. (Premix and supplement labels only).
5. Do not use thixotropic supplements after four weeks storage. (Cargill thixotropic liquid supplement labels only).
6. Do not use thixotropic supplements after eight weeks storage. (Westway Feed Products, A Division of Westway Holdings Canada Inc., thixotropic liquid supplement labels only).

Claim 5: For increased rate of weight gain in growing cattle on pasture (slaughter, stocker and feeder cattle, and beef and dairy replacement heifers) of greater than 180 kg (400 lb) body weight.

Level of Drug:

200 mg of monensin activity per head per day.

Directions:

Hand feed continuously a minimum of 0.5 kg of medicated supplement per day to supply 200 mg of monensin activity per head per day. The medicated supplement must be hand fed from the beginning to the end of the pasture season.

Note:

Thixotrope liquid medicated supplements should not be used for hand feeding of cattle on pasture.

Warning:

1. Do not supplement monensin from other sources (e.g. other feed stuffs containing monensin or the Rumensin Controlled Release Capsule).

Caution:

1. Do not exceed recommended levels as reduced average daily gains may result.
2. Do not allow dogs, horses or other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
3. Do not use monensin-medicated feed for the treatment of outbreaks of coccidiosis.
4. May be used in feeds containing the pellet-binding agents Bentonite (2%), Attapulgite (2%), Kaolin (2.5%), Lignin Sulfonate (4%), Carboxymethyl cellulose (0.1%), or Agri-Colloid. (Premix and Supplement labels only).

Claim 6: For reduction of milk fat percentage in lactating dairy cows.

Note:

The expected efficacy of this product for reduction of milk fat percentage may be affected by dietary factors. Reduced efficacy may be expected with diets higher in fibre or lower in unsaturated oils.

Level of Drug:

Monensin activity 16 mg/kg  - 24 mg/kg  (0.0016%-0.0024%) in the complete diet.

Note:

1. Feed labels must state one specific drug level.
2. Complete diet refers to the complete feed plus the roughage and must be corrected to a 100% dry matter basis.

Directions:

At a level in supplements, premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Thoroughly mix supplements and premixes in the total daily diet or in complete feed (grain portion of the ration) before use. Do not feed undiluted.

Medicated supplement/premix fed as a % of total diet dry matter:

Mixing medicated supplements or premixes as a % of total diet dry matter is ideal. The following calculation can be used to assist in determining the amount of monensin sodium required per kg of supplement/premix dry matter to meet the approved level of drug in the total diet dry matter;

mg monensin/kg supplement/premix dry matter = (approved drug level (mg/kg  total diet Dry Matter)) / (% inclusion of supplement/premix into diet on a 100% dry matter basis) x 100

Medicated supplement/premix fed as a fixed amount/ head/ day:

It may sometimes be preferable to mix the medicated supplement/premix in the complete feed or total diet as a fixed amount/head/day. The approved levels of monensin sodium must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg/head/day = weight of animal (kg) x dry matter intake (% of body weight) x approved drug level (mg/kg  total diet Dry Matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Medicated complete feeds:

Medicated complete feeds are often fed separately from the forage part of the ration on a fixed amount/head/day. The approved levels of monensin sodium must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg  total diet Dry Matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Note:

RUMENSIN PREMIX and COBAN PREMIX only can be used in the following thixotrope liquid supplements:

1. HCS, Nutrena Feeds, Cargill Limited;
2. Promolas Liquid Supplement Suspension, Westway Feed Products, a Division of Westway Holdings Canada Inc.

Warning:

1. Do not supplement monensin from other sources (e.g. other feed stuffs containing monensin or the Rumensin Controlled Release Capsule).

Caution:

1. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
2. May be used in feeds containing the pellet-binding agents Bentonite (2%), Attapulgite (2%), Kaolin (2.5%), Lignin Sulfonate(4%), Carboxymethyl cellulose (0.1%), or Agri-Colloid. (Premix and supplement labels only).
3. Do not use thixotropic supplements after four weeks storage. (Cargill thixotropic liquid supplement labels only).
4. Do not use thixotropic supplements after eight weeks storage. (Westway Feed Products, A Division of Westway Holdings Canada Inc., thixotropic liquid supplement labels only).
5. The 24 g/tonne monensin treatment in primiparous cows may result in the increased incidence of udder edema and increased number of inseminations per full term conception.
6. The continuous use of monensin in dairy cows may be associated with increased rates of twinning and stillbirths, and heavier birth weights for heifer calves.

Claim 7: For minimizing loss of body condition during lactation in dairy cows.

Level of Drug:

Monensin activity 8 mg/kg  - 24 mg/kg  (0.0008%-0.0024%) in the complete diet.

Note:

1. Feed labels must state one specific drug level.
2. Complete diet refers to the complete feed plus the roughage and must be corrected to a 100% dry matter basis.

Directions:

At a level in supplements, premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Thoroughly mix supplements and premixes in the total daily diet or in complete feed (grain portion of the ration) before use. Feed continuously during the dry and lactating periods. Do not feed undiluted.

Medicated supplement/premix fed as a % of total diet dry matter:

Mixing medicated supplements or premixes as a % of total diet dry matter is ideal. The following calculation can be used to assist in determining the amount of monensin sodium required per kg of supplement/premix dry matter to meet the approved level of drug in the total diet dry matter;

mg monensin/kg supplement/premix dry matter = (approved drug level (mg/kg  total diet Dry Matter)) / (% inclusion of supplement/premix into diet on a 100% dry matter basis) x 100

Medicated supplement/premix fed as a fixed amount/ head/ day:

It may sometimes be preferable to mix the medicated supplement/premix in the complete feed or total diet as a fixed amount/head/day. The approved levels of monensin sodium must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg/head/day = weight of animal (kg) x dry matter intake (% of body weight) x approved drug level (mg/kg  total diet Dry Matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Medicated complete feeds:

Medicated complete feeds are often fed separately from the forage part of the ration on a fixed amount/head/day. The approved levels of monensin sodium must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg  total diet Dry Matter)

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Note:

RUMENSIN PREMIX and COBAN PREMIX only can be used in the following thixotrope liquid supplements:

1. HCS, Nutrena Feeds, Cargill Limited;
2. Promolas Liquid Supplement Suspension, Westway Feed Products, a Division of Westway Holdings Canada Inc.

Warning:

1. Do not supplement monensin from other sources (e.g. other feed stuffs containing monensin or the Rumensin Controlled Release Capsule).

Caution:

1. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
2. May be used in feeds containing the pellet-binding agents Bentonite (2%), Attapulgite (2%), Kaolin (2.5%), Lignin Sulfonate(4%), Carboxymethyl cellulose (0.1%), or Agri-Colloid. (Premix and supplement labels only).
3. Do not use thixotropic supplements after four weeks storage. (Cargill thixotropic liquid supplement labels only).
4. Do not use thixotropic supplements after eight weeks storage. (Westway Feed Products, A Division of Westway Holdings Canada Inc., thixotropic liquid supplement labels only).
5. The 24 g/tonne monensin treatment in primiparous cows may result in the increased incidence of udder edema and increased number of inseminations per full term conception.
6. The continuous use of monensin in dairy cows may be associated with increased rates of twinning and stillbirths, and heavier birth weights for heifer calves.

Claim 8: For improving feed efficiency of milk protein production in lactating dairy cows.

Level of Drug:

Monensin activity 16 mg/kg  - 24 mg/kg  (0.0016%-0.0024%) in the complete diet.

Note:

1. Feed labels must state one specific drug level.
2. Complete diet refers to the complete feed plus the roughage and must be corrected to a 100% dry matter basis.

Directions:

At a level in supplements, premixes, and complete feeds so that when used as directed, the approved level of drug will be supplied.

Thoroughly mix supplements and premixes in the total daily diet or in complete feed (grain portion of the ration) before use. Do not feed undiluted.

Medicated supplement/premix fed as a % of total diet dry matter:

Mixing medicated supplements or premixes as a % of total diet dry matter is ideal. The following calculation can be used to assist in determining the amount of monensin sodium required per kg of supplement/premix dry matter to meet the approved level of drug in the total diet dry matter;

mg monensin/kg supplement/premix dry matter = (approved drug level (mg/kg  total diet Dry Matter)) / (% inclusion of supplement/premix into diet on a 100% dry matter basis) x 100

Medicated supplement/premix fed as a fixed amount/ head/ day:

It may sometimes be preferable to mix the medicated supplement/premix in the complete feed or total diet as a fixed amount/head/day. The approved levels of monensin sodium must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg/head/day = weight of animal (kg) x dry matter intake (% of body weight) x approved drug level (mg/kg  total diet Dry Matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Medicated complete feeds:

Medicated complete feeds are often fed separately from the forage part of the ration on a fixed amount/head/day. The approved levels of monensin sodium must be converted to mg/head/day to accommodate this type of feeding. To do this, the following calculation is used:

mg monensin/head/day = weight of animal (kg) x dry matter intake (as a % of body weight) x approved drug level (mg/kg  total diet Dry Matter).

Note that feed labels will be required to state both the body weight of the cattle being fed as well as their dry matter intake.

Note:

Rumensin Premix and COBAN Premix only can be used in the following thixotrope liquid supplements:

1. HCS, Nutrena Feeds, Cargill Limited;
2. Promolas Liquid Supplement Suspension, Westway Feed Products, a Division of Westway Holdings Canada Inc.
   

Warning:

1. Do not supplement monensin from other sources (e.g. other feed stuffs containing monensin or the Rumensin Controlled Release Capsule).

Caution:

1. Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Ingestion of monensin by these species has been fatal.
2. May be used in feeds containing the pellet-binding agents Bentonite (2%), Attapulgite (2%), Kaolin (2.5%), Lignin Sulfonate(4%), Carboxymethyl cellulose (0.1%), or Agri-Colloid. (Premix and supplement labels only).
3. Do not use thixotropic supplements after four weeks storage. (Cargill thixotropic liquid supplement labels only).
4. Do not use thixotropic supplements after eight weeks storage. (Westway Feed Products, A Division of Westway Holdings Canada Inc., thixotropic liquid supplement labels only).
5. The 24 g/tonne monensin treatment in primiparous cows may result in the increased incidence of udder edema and increased number of inseminations per full term conception.
6. The continuous use of monensin in dairy cows may be associated with increased rates of twinning and stillbirths, and heavier birth weights for heifer calves.

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Accepted Compatibilities

Monensin sodium is compatible with the following drugs/drug combinations. For details refer to the MIB as indicated.

Number	Medicated ingredients	For use in feed for
1.	Melengestrol acetate (MIB #46)	beef heifers 181 kg and over
2.	Bacitracin methylene disalicylate (MIB #48)	broiler chickens
3.	Bambermycins (MIB #10.12)	broiler chickens
4.	Tylosin Phosphate (MIB #43) (cleared with monensin sodium at 11 mg/kg and 33 mg/kg in complete diets including roughage [100% dry matter basis] only).	beef cattle
5.	Lincomycin (MIB #10.5)	broiler chickens
6.	Lincomycin (MIB #10.5) and 3-nitro-4-hydroxyphenylarsonic acid (MIB #21)	broiler chickens
7.	3-nitro-4-hydroxyphenylarsonic acid (MIB #21)	broiler chickens
8.	Virginiamycin (MIB #10.11)	broiler chickens