LINCOMYCIN - MIB #68

Date Revised: 2009-08

Approved Brands

1. LINCOMIX 44 PREMIX contains lincomycin (as lincomycin hydrochloride at 44 g/kg (Pfizer Canada Inc.)
2. LINCOMIX 110 PREMIX contains lincomycin (as lincomycin hydrochloride) at 110 g/kg (Pfizer Canada Inc.)
3. LINCOMYCIN 44 PREMIX contains lincomycin (as lincomycin hydrochloride) at 44 g/kg (Bio Agri Mix Ltd.)
4. LINCOMYCIN 110 PREMIX contains lincomycin (as lincomycin hydrochloride) at 110 g/kg (Bio Agri Mix Ltd.)
5. LINCOMYCIN 44 G PREMIX contains lincomycin (as lincomycin hydrochloride) at 44 g/kg (Bio Agri Mix Ltd.)
6. LINCOMYCIN 110 G PREMIX contains lincomycin (as lincomycin hydrochloride) at 110 g/kg (Bio Agri Mix Ltd.)

Approved for use

In meal or pellet feed for swine.

Note: LINCOMYCIN 44 PREMIX; LINCOMYCIN 110 PREMIX; LINCOMYCIN 44G PREMIX; and LINCOMYCIN 110G PREMIX are approved ONLY for claims 1 and 2.

Approved claims

For swine - Claims 1, 2, 3.

Claim 1: To reduce the severity of Mycoplasmal Pneumonia in growing swine.

Level of Drug: 220 mg/kg (0.022%) of complete feed.

Directions: Feed this medicated feed to growing swine as the sole ration for 21 days.

Warning:

1. Treated animals must not be slaughtered for use in food for at least one (1) day after the latest treatment with this medicated feed.

Caution:

1. Treated pigs may develop some stool softening or mild diarrhea within 36 hours of treatment initiation. Signs of mild irritation and swelling of the anus and/or vulva may be associated with the stool changes. On rare occasions some pigs can show reddening of the skin and irritable behavior. Should these reactions be more severe than described above, discontinue the use of the medicated feed.
2. Not for use in breeding swine.
3. Do not allow rabbits, hamsters, guinea pigs, horses, dairy cattle or other ruminants access to feeds containing lincomycin. Ingestion by these species may result in severe gastrointestinal effects or metabolic disorders (e.g. Ketosis in dairy cattle).
4. Do not use in feed containing pellet-binding agents except Lignin Sulfonate (required on premix and supplement labels only).
5. Good manufacturing practices should be observed in preparing feeds containing lincomycin. This includes appropriate clean-out procedures to avoid cross contamination. Premixes containing lincomycin must be thoroughly mixed in feed before use (required on premix and supplement labels only).

Claim 2: For the treatment of Swine Dysentery (Bloody Scours) associated with Treponema hyodysenteriae in growing swine, and for the control of the disease following treatment.

Level of Drug:

1. 110 mg/kg (0.011%) of the complete feed for 21 days or until signs of the disease disappear, followed by:
2. 44 mg/kg (0.0044%) of the complete feed for a further 4 weeks.

Directions:

1. Feed 110 mg/kg medicated feed as the sole ration for 21 days or until signs of the disease (watery, mucoid or bloody stools) disappear. This must be followed by 44 mg/kg medicated feed for the next four weeks.
2. Feed 44 mg/kg medicated feed as the sole ration for the next 4 weeks only after having fed 110 mg/kg medicated feed for 21 days or until signs of disease (watery or bloody stools) disappear.

Note: Retreat with the above dosage regimen if the signs of swine dysentery reappear.

Caution:

1. Treated pigs may develop some stool softening or mild diarrhea within 36 hours of treatment initiation. Signs of mild irritation and swelling of the anus and/or vulva may be associated with the stool changes. On rare occasions some pigs can show reddening of the skin and irritable behavior. Should these reactions be more severe than described above, discontinue the use of the medicated feed.
2. Not for use in breeding swine.
3. Do not allow rabbits, hamsters, guinea pigs, horses, dairy cattle or other ruminants access to feeds containing lincomycin. Ingestion by these species may result in severe gastrointestinal effects or metabolic disorders (e.g. Ketosis in dairy cattle).
4. Do not use in feed containing pellet-binding agents except Lignin sulfonate (required on premix and supplement labels only).
5. Good manufacturing practices should be observed in preparing feeds containing lincomycin. This includes appropriate clean-out procedures to avoid cross contamination. Premixes containing lincomycin must be thoroughly mixed in feed before use (required on premix and supplement labels only).

Claim 3: As an aid in reducing the clinical severity of Porcine Proliferative Enteropathy (lleitis) associated with Lawsonia intracellularis.

Level of Drug:

1. 110 mg/kg (0.011%) of the complete feed.

Directions:

1. Feed 110 mg/kg medicated feed as the sole ration for 21 days.

Note to User (Not required on feed labels): Only LINCOMIX 44 PREMIX and LINCOMIX 110 PREMIX are approved for claim 3.

Caution:

1. Treated pigs may develop some stool softening or mild diarrhea within 36 hours of treatment initiation. Signs of mild irritation and swelling of the anus and/or vulva may be associated with the stool changes. On rare occasions some pigs can show reddening of the skin and irritable behaviour. Should these reactions be more severe than described above, discontinue the use of the medicated feed.
2. Not for use in breeding swine.
3. Do not allow rabbits, hamsters, guinea pigs, horses, dairy cattle or other ruminants access to feeds containing lincomycin. Ingestion by these species may result in severe gastrointestinal effects or metabolic disorders (e.g. Ketosis in dairy cattle).
4. Do not use in feed containing pellet-binding agents except Lignin sulfonate (required on premix and supplement labels only).
5. Good manufacturing practices should be observed in preparing feeds containing lincomycin. This includes appropriate clean-out procedures to avoid cross contamination. Premixes containing lincomycin must be thoroughly mixed in feed before use (required on premix and supplement labels only).

Accepted Compatibilities

Nil Lincomycin is compatible with the following drug/drug combinations. For details refer to the MIB as indicated.