SALINOMYCIN SODIUM - MIB #69

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Date Revised: 2010-01

Approved Brands

1. COXISTAC 6% PREMIX contains salinomycin sodium at 60 g/kg (Phibro Animal Health Ltd.)
2. COXISTAC 12% PREMIX contains salinomycin sodium at 120 g/kg (Phibro Animal Health Ltd.)
3. POSISTAC 6% PREMIX contains salinomycin sodium at 60 g/kg (Phibro Animal Health Ltd.)
4. SACOX 120 MEDICATED PREMIX contains salinomycin sodium at 120 g/kg (Huvepharma)
5. SALINOMYCIN 60 PREMIX contains salinomycin sodium at 60 g/kg (Bio Agri Mix Ltd.)
6. BIO-COX 120 G PREMIX contains salinomycin sodium at 120 g/kg (Alpharma Canada Corporation)
7. BIO-COX 120 G PLUS PREMIX contains salinomycin sodium at 120 g/kg (Alpharma Canada Corporation)

Approved for use

In meal or pellet feed for broiler chickens and beef cattle (steers and feedlot heifers).

Note:

COXISTAC 6% PREMIX, COXISTAC 12% PREMIX, SACOX 120 MEDICATED PREMIX, SALINOMYCIN 60 PREMIX, BIO-COX 120 G PREMIX and BIO-COX 120 G PLUS PREMIX are approved for use only in feeds for broiler chickens.

POSISTAC 6% PREMIX is approved for use only in feeds for beef cattle (steers) and Feedlot heifers.

Approved claims

For broiler chickens - Claim 1
For beef cattle (steers) - Claim 2
For Feedlot heifers (when fed with MGA 100 Premix) - Claim 3

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Claim 1: As an aid in the prevention of Coccidiosis caused by Eimeria acervulina, E. mitis, E. necatrix, E. maxima, E. tenella and E. brunetti in broiler chickens.

Level of Drug:

60 mg/kg (0.006%) of complete feed.

Directions:

This medicated feed is to be fed continuously as the sole ration up to marketing.

Warning:

1. Do not feed to replacement, laying or breeding chickens.

Caution:

1. Do not allow turkeys, dogs or horses access to this medicated feed as it is known to be toxic to these species. Extra care should be taken to avoid contamination of feeds for these animals.
2. A weight gain reduction may occur in cockerels fed this medicated feed in the absence of coccidial exposure.
3. Do not administer tiamulin to birds receiving this medicated feed.
4. Do not use in feeds containing pellet binding agents with the exception of Lignosol and Agri-Colloid (Required on supplement and premix labels containing COXISTAC 6% PREMIX or COXISTAC 12% PREMIX )
5. Do not use in feeds containing pellet binding agents (Required on supplement and premix labels containing BIO-COX 120 G PREMIX, SACOX 120 MEDICATED PREMIX or SALINOMYCIN 60 PREMIX)
6. Do not use this feed for treatment of outbreaks of Coccidiosis.
7. Consult a veterinarian or poultry pathologist if losses exceed 0.5% in a two day period.

Claim 2: For the improvement of feed efficiency in steers fed in confinement for slaughter

Level of Drug:

In complete diets, supplements and premixes at a level which, when fed as directed, will provide 100 mg of salinomycin sodium per head per day. The following tables may be used as a guide:

Note:

Complete diet refers to the complete feed plus the roughage and must be corrected to a 100% dry matter basis.

A. Complete diet

Weight of steers (kg)	Estimated daily dry matter intake (kg)	Recommended salinomycin concentration (mg/kg)
220 to 300	6.25	16
301 to 400	7.70	13
Over 400	9.00	11

Note: To ensure proper mixing, the drug premix should first be diluted with grain or supplement in an intermediate blending step prior to adding to the final blend of complete diet.

B. Supplements

Supplement Feeding Rate (kg/head/day)	Recommended salinomycin sodium concentration (mg/kg)
0.5	200
1.0	100
1.5	66
2.0	50

Directions:

Thoroughly mix the medicated supplement in the total daily diet or in the complete feed (grain portion of the ration) before use. Feed continuously to steers during their entire confinement period. Do not feed undiluted.

Caution:

1. Do not allow dogs, horses or turkeys access to this medicated feed as it is known to be toxic to these species. Extra care should be taken to avoid contamination of feeds for these animals.
2. Do not administer tiamulin to animals receiving this medicated feed.
3. Do not use in feeds containing pellet-binding agents with the exception of Lignosol and Agri-Colloid. (Required on Supplement and premix labels only).
4. Do not administer to replacement or breeding cattle, to calves below 220 kg body weight, or to lactating dairy cattle.

Claim 3: For the improved growth rate and feed efficiency, and an aid in suppression of estrus in beef heifers being fed for slaughter.

Note:

This claim only applies when salinomycin sodium is administered concurrently with melengestrol acetate at 0.40 mg/head/day.

Level of Drug:

In complete diets, supplements and premixes for beef heifers 220 kg body weight and heavier, at a level which, when fed as directed, will provide 100 mg of salinomycin sodium and 0.40 mg melengestrol acetate per head per day. The following tables may be used as a guide:

Note:

Complete diet refers to the complete feed plus the roughage and must be corrected to a 100% dry matter basis.

A. Complete diet

Weight of heifers (kg)	Estimated daily dry matter intake (kg)	Recommended salinomycin concentration (mg/kg)
220 to 300	6.25	16
301 to 400	7.70	13
Over 400	9.00	11

Note: To ensure proper mixing, the drug premix should first be diluted with grain or supplement in an intermediate blending step prior to adding to the final blend of complete diet.

B. Supplements

Supplement Feeding Rate (kg/head/day)	Recommended salinomycin sodium concentration (mg/kg)
0.5	200
1.0	100
1.5	66
2.0	50

Directions:

Thoroughly mix the medicated supplement/premix in the total daily diet or in the complete feed (grain portion of the ration) before use. Feed continuously to beef heifers during their entire confinement period. Do not feed undiluted.

Warning:

1. Treated feedlot heifers must not be slaughtered for food for at least 24 hours after the last treatment with this medicated feed.

Caution:

1. Do not allow dogs, horses or turkeys access to this medicated feed as it is known to be toxic to these species. Extra care should be taken to avoid contamination of feeds for these animals
2. Do not administer tiamulin to animals receiving this medicated feed.
3. Do not use in feeds containing pellet-binding agents with the exception of Lignosol, and Agri-Colloid. (Required on Supplement and Premix labels only).
4. Do not administer to replacement or breeding cattle, to calves below 220 kg body weight, or to lactating dairy cattle.

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Accepted Compatibilities

Salinomycin sodium is compatible with the following drugs/drug combinations. For details refer to the MIB as indicated.

Number	Medicated ingredients	For use in feed for
1.	Bambermycins (MIB #10.12)	broiler chickens
2.	Lincomycin (MIB #10.5)	broiler chickens
3.	Virginiamycin (MIB #10.11)	broiler chickens
4.	Bacitracin Methylene Disalicylate (MIB #48)	broiler chickens
5.	Melengestrol acetate (MIB #46)	feedlot heifers