Notice to industry - CFIA Monitoring of Fluoroquinolones and Tetracyclines in Fish and Crustaceans Products

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May 4, 2017 – Ottawa, ON – Canadian Food Inspection Agency

The purpose of this notice is to advise industry that the Canadian Food Inspection Agency (CFIA) is expanding the scope of testing for two analyses in therapeutants monitoring for aquacultured fish and crustaceans.

  • The fluoroquinolones analysis will be expanded to include the new compounds marbofloxacin, difloxacin, orbifloxacin and norfloxacin.
  • The tetracyclines analysis will be expanded to include the new compound doxycycline.

As of May 22nd, 2017, the CFIA will begin testing aquacultured fish and crustaceans for these compounds, in addition to the therapeutants it currently tests.

Expanding the scope will improve monitoring for therapeutant use in aquaculture.

What this means for you

The CFIA reminds importers and domestic processors of their legal responsibility to ensure that the aquacultured fish and fish products they import or process meet Canadian regulatory requirements.

According to the Food and Drug Regulations, residues of these compounds are not permitted to be used in fish product intended for consumption as food. Aquacultured products containing these residues are in violation of the Fish Inspection Regulations and the Food and Drugs Act. The CFIA will take appropriate regulatory action on non-compliant products.

The CFIA encourages importers and processors to:

  • communicate with your suppliers regarding therapeutant use in aquaculture products you market, and
  • maintain updated product specifications described in buyer-seller agreements and/or Hazard Analysis Critical Control Point (HACCP) plans.

If you are a Quality Management Program (QMP) importer or processor, you should ensure that your QMP plan is updated to include the monitoring of these additional therapeutants.

More information

  • For more information on Canadian requirements related to therapeutant use in aquaculture, refer to the CFIA's Fish Products Standards and Methods Manual, Appendix 1(A) – CFIA Aquaculture Therapeutant Residue Monitoring List.
  • For more information on the analytical method for determination of these fluoroquinolone and tetracycline compounds and associated method performance specifications, contact Jeffrey Van de Riet, National Manager, Food Chemistry Laboratory Coordination by email at
  • If you have other questions, contact your local CFIA office.
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