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Lincomycin and Spectinomycin (LISP) – Medicating Ingredient Brochure

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Status: Veterinary prescription required for approved claims

Date of revision: April 2018

Table of approved species and claims
Approved livestock species Approved claim(s)
(abbreviated)Table note 1
Withdrawal time Name of approved brand(s)
Swine
  1. Prevention of swine dysentery
24 hours (meat)
  1. L-S 20 Premix
  2. Lincomycin Spectinomycin 4.4% G Premix

Swine

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claims 1
  1. L-S 20 Premix
  • Lincomycin base (as lincomycin hydrochloride) at 22 g/kg
  • Spectinomycin base (as spectinomycin sulfate) at 22 g/kg
Claims 1
  1. Lincomycin Spectinomycin 4.4% G Premix
  • Lincomycin base (as lincomycin hydrochloride) at 22 g/kg
  • Spectinomycin base (as spectinomycin hydrochloride) at 22 g/kg

Claim 1

For the prevention of swine dysentery in growing swine up to a weight of 57 kg.

Level of medicating ingredient in a complete feed

22 mg/kg (0.0022%) lincomycin and 22 mg/kg (0.0022%) spectinomycin in the complete feed.

Directions for use in a complete feed

This livestock feed contains a medically important antibiotic. To reduce the development of antimicrobial resistance and maintain effectiveness, use this antibiotic prudently and for the shortest duration required to achieve the desired clinical outcome.

Feed this medicated feed as the sole ration to growing swine up to a weight of 57 kg.

Additional information (not to appear on feed labels)

For feed manufacturers
Add and mix thoroughly into the ration at the following rate to provide 22 mg/kg (0.0022%) lincomycin and 22 mg/kg (0.0022%) spectinomycin per metric tonne (1000 kg) of finished (complete) feed:

Warning

  1. Treated swine must not be slaughtered for use in food for at least 24 hours after the latest treatment with this medicated feed when fed at the recommended level of 22 mg/kg lincomycin and 22 mg/kg spectinomycin in the complete feed.
  2. When handling the product, avoid inhalation, oral exposure and direct contact with skin or eyes. (Required on premix and supplement labels only)
  3. Keep out of reach of children. (Required on premix and supplement labels only)

Caution

  1. Do not allow rabbits, hamsters, guinea pigs, horses, dairy cattle or other ruminants access to feeds containing lincomycin. Ingestion by these species may result in severe gastrointestinal effects or metabolic disorders (e.g. Ketosis in dairy cattle).
  2. Good manufacturing practices should be observed in preparing feeds containing lincomycin. This includes appropriate clean-out procedures to avoid cross contamination. (Required on premix and supplement labels only)
  3. Only for use in growing swine up to 57 kg bodyweight.
  4. Treated pigs may develop some stool softening or mild diarrhea within 36 hours of treatment initiation. Signs of mild irritation and swelling of the anus and/or vulva may be associated with the stool changes. These adverse reactions are transient and self-correcting by the fifth to eighth day of treatment. Should these reactions be more severe than described above discontinue the use of the drug.
  5. Feed only to swine intended for slaughter.

Accepted Compatibilities

Nil

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